COVID-19 >>"True and Helpful" Covid Information Thread

[cc]

That item I posted a few days ago told it in exact numbers for Delta variant (most cases) - I'm not sure where it is



If I recall correctly, Pfizer 88% effective against delta ... AZ was less so

Okay, I'll have a look.

Here it is

Finally some data on effectiveness against Delta Variant (Again, it's only one. More are needed to be sure what is happening)

However, this one describes its methods extensively as pdf shows.

It is totally different result than that Israeli one that gave no data on methodology & examines far more cases very scientifically



The new england journal of medicine



Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

Jamie Lopez Bernal, F.F.P.H., Ph.D., Nick Andrews, Ph.D.,

Charlotte Gower, D.Phil., Eileen Gallagher, Ph.D., Ruth Simmons, Ph.D.,

Simon Thelwall, Ph.D., Julia Stowe, Ph.D., Elise Tessier, M.Sc.,

Natalie Groves, M.Sc., Gavin Dabrera, M.B., B.S., F.F.P.H., Richard Myers, Ph.D.,

Colin N.J. Campbell, M.P.H., F.F.P.H., Gayatri Amirthalingam, M.F.P.H.,

Matt Edmunds, M.Sc., Maria Zambon, Ph.D., F.R.C.Path.,

Kevin E. Brown, M.R.C.P., F.R.C.Path., Susan Hopkins, F.R.C.P., F.F.P.H.,

Meera Chand, M.R.C.P., F.R.C.Path., and Mary Ramsay, M.B., B.S., F.F.P.H.



NOTE: "BNT162b2" is PHIZER ..... "2ChAdOx1 nCoV-19)" is AstraZeneca



BACKGROUND

The B.1.617.2 (delta) variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), has contributed to a surge in cases in India and has now been detected across the globe, including a notable increase in cases in the United Kingdom. The effectiveness of the BNT162b2 and ChAdOx1 nCoV-19 vaccines against this variant has been unclear.



METHODS

We used a test-negative case–control design to estimate the effectiveness of vaccination against symptomatic disease caused by the delta variant or the predominant strain (B.1.1.7, or alpha variant) over the period that the delta variant began

circulating. Variants were identified with the use of sequencing and on the basis

of the spike (S) gene status. Data on all symptomatic sequenced cases of Covid-19

in England were used to estimate the proportion of cases with either variant according to the patients' vaccination status.



RESULTS - SHORT FORM in Layman terms:(I shortened it to get to the meat of it)



Effectiveness after one dose of vaccine (BNT162b2 or ChAdOx1 nCoV-19) was notably lower among persons with the delta variant cthan among those with the alpha variant - (you can read pdf for detail as the way it was presented - I did not understand and could not decipher effectiveness)



 However, this was clear >

1. With the BNT162b2 vaccine, the effectiveness of two doses was 93.7% among persons with the alpha variant and 88.0% among those with the delta variant.

2. With the ChAdOx1 nCoV-19 vaccine, the effectiveness of two doses was 74.5% (among persons with the alpha variant and 67.0% among those with the delta variant.



CONCLUSIONS

Only modest differences in vaccine effectiveness were noted with the delta variant as compared with the alpha variant after the receipt of two vaccine doses. Absolute differences in vaccine effectiveness were more marked after the receipt of the first dose.



This finding would support efforts to maximize vaccine uptake with two doses among vulnerable populations. (Funded by Public Health England.)



PDF FILE > https://www.nejm.org/doi/pdf/10.1056/NEJMoa2108891?articleTools=true">https://www.nejm.org/doi/pdf/10.1056/NE ... Tools=true">https://www.nejm.org/doi/pdf/10.1056/NEJMoa2108891?articleTools=true

[Anonymous]

Here it is

Finally some data on effectiveness against Delta Variant (Again, it's only one. More are needed to be sure what is happening)

However, this one describes its methods extensively as pdf shows.

It is totally different result than that Israeli one that gave no data on methodology & examines far more cases very scientifically



The new england journal of medicine



Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

Jamie Lopez Bernal, F.F.P.H., Ph.D., Nick Andrews, Ph.D.,

Charlotte Gower, D.Phil., Eileen Gallagher, Ph.D., Ruth Simmons, Ph.D.,

Simon Thelwall, Ph.D., Julia Stowe, Ph.D., Elise Tessier, M.Sc.,

Natalie Groves, M.Sc., Gavin Dabrera, M.B., B.S., F.F.P.H., Richard Myers, Ph.D.,

Colin N.J. Campbell, M.P.H., F.F.P.H., Gayatri Amirthalingam, M.F.P.H.,

Matt Edmunds, M.Sc., Maria Zambon, Ph.D., F.R.C.Path.,

Kevin E. Brown, M.R.C.P., F.R.C.Path., Susan Hopkins, F.R.C.P., F.F.P.H.,

Meera Chand, M.R.C.P., F.R.C.Path., and Mary Ramsay, M.B., B.S., F.F.P.H.



NOTE: "BNT162b2" is PHIZER ..... "2ChAdOx1 nCoV-19)" is AstraZeneca



BACKGROUND

The B.1.617.2 (delta) variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), has contributed to a surge in cases in India and has now been detected across the globe, including a notable increase in cases in the United Kingdom. The effectiveness of the BNT162b2 and ChAdOx1 nCoV-19 vaccines against this variant has been unclear.



METHODS

We used a test-negative case–control design to estimate the effectiveness of vaccination against symptomatic disease caused by the delta variant or the predominant strain (B.1.1.7, or alpha variant) over the period that the delta variant began

circulating. Variants were identified with the use of sequencing and on the basis

of the spike (S) gene status. Data on all symptomatic sequenced cases of Covid-19

in England were used to estimate the proportion of cases with either variant according to the patients' vaccination status.



RESULTS - SHORT FORM in Layman terms:(I shortened it to get to the meat of it)



Effectiveness after one dose of vaccine (BNT162b2 or ChAdOx1 nCoV-19) was notably lower among persons with the delta variant cthan among those with the alpha variant - (you can read pdf for detail as the way it was presented - I did not understand and could not decipher effectiveness)



 However, this was clear >

1. With the BNT162b2 vaccine, the effectiveness of two doses was 93.7% among persons with the alpha variant and 88.0% among those with the delta variant.

2. With the ChAdOx1 nCoV-19 vaccine, the effectiveness of two doses was 74.5% (among persons with the alpha variant and 67.0% among those with the delta variant.



CONCLUSIONS

Only modest differences in vaccine effectiveness were noted with the delta variant as compared with the alpha variant after the receipt of two vaccine doses. Absolute differences in vaccine effectiveness were more marked after the receipt of the first dose.



This finding would support efforts to maximize vaccine uptake with two doses among vulnerable populations. (Funded by Public Health England.)



PDF FILE > https://www.nejm.org/doi/pdf/10.1056/NEJMoa2108891?articleTools=true">https://www.nejm.org/doi/pdf/10.1056/NE ... Tools=true">https://www.nejm.org/doi/pdf/10.1056/NEJMoa2108891?articleTools=true

All the info we need.

[Anonymous]

Cases rising a little in Canada.

[Anonymous]

Cases rising a little in Canada.

Nothing to be alarmed about.

[cc]

https://www.ctvnews.ca/health/coronavirus/quebec-offers-extra-dose-to-travellers-whose-vaccination-status-isn-t-recognized-1.5523936">Quebec offers extra dose to travellers whose vaccination status isn't recognized



MONTREAL — Quebec is offering an extra dose of mRNA vaccine to people who want to travel to countries that don't recognize their vaccination status.



A third dose is being made available because some countries don't consider people fully vaccinated if they have received a mix of COVID-19 vaccines, the Health Department said Monday.



Essentially WHO & the rest of the world does not consider anyone in Canada to be fully vaccinated thanks to Mixy Matchy Madness. Thanks Mr. Government.



https://globalnews.ca/news/8060025/ontario-asks-feds-mixing-covid-vaccines-travel/">Ontario asks feds to work with WHO on ensuring mixed COVID-19 vaccines recognized abroad

[Anonymous]

https://server9.kproxy.com/servlet/redirect.srv/sfi/safoyhgq/smno/p2/health/coronavirus/quebec-offers-extra-dose-to-travellers-whose-vaccination-status-isn-t-recognized-1.5523936">Quebec offers extra dose to travellers whose vaccination status isn't recognized



MONTREAL — Quebec is offering an extra dose of mRNA vaccine to people who want to travel to countries that don't recognize their vaccination status.



A third dose is being made available because some countries don't consider people fully vaccinated if they have received a mix of COVID-19 vaccines, the Health Department said Monday.



Essentially WHO & the rest of the world does not consider anyone in Canada to be fully vaccinated thanks to Mixy Matchy Madness. Thanks Mr. Government.



https://server9.kproxy.com/servlet/redirect.srv/sfi/safoyxnpdbx/p2/news/8060025/ontario-asks-feds-mixing-covid-vaccines-travel/">Ontario asks feds to work with WHO on ensuring mixed COVID-19 vaccines recognized abroad

I'm in that boat.

[cc]

Yes. Thot about you when I posted. I think they will get it worked out by agreement or 3rd dose - we do have the stock

[cc]

Yes. Thot about you when I posted. I think they will get it worked out by agreement or 3rd dose - we do have the stock





WOWZERS - More good Vax stats from BC - They just completed thorough accounting for last 2 months



1. 96 % of all infected had no vaccine along with a very few who had only single dose



2. 78% of those hospitalized are completely unvaccinated & a further 18 % has one dose

(leaving only 4% for those double-vaxxed )



Seems maybe the single dose for many in lieu of early double dose may not have been such a good plan .. although antibody tests show more antibodies for those who had a delay between shots?



My guess is, with quantities strong now, they will give a 3rd shot to elders and care homes sooner rather than later

[Anonymous]

https://server9.kproxy.com/servlet/redirect.srv/sfi/safoyhgq/smno/p2/health/coronavirus/quebec-offers-extra-dose-to-travellers-whose-vaccination-status-isn-t-recognized-1.5523936">Quebec offers extra dose to travellers whose vaccination status isn't recognized



MONTREAL — Quebec is offering an extra dose of mRNA vaccine to people who want to travel to countries that don't recognize their vaccination status.



A third dose is being made available because some countries don't consider people fully vaccinated if they have received a mix of COVID-19 vaccines, the Health Department said Monday.



Essentially WHO & the rest of the world does not consider anyone in Canada to be fully vaccinated thanks to Mixy Matchy Madness. Thanks Mr. Government.



https://server9.kproxy.com/servlet/redirect.srv/sfi/safoyxnpdbx/p2/news/8060025/ontario-asks-feds-mixing-covid-vaccines-travel/">Ontario asks feds to work with WHO on ensuring mixed COVID-19 vaccines recognized abroad

I'm in that boat.

You better get a third dose(second MRNA) if you want a winter trip.

[cc]

This is being pressed now - they will get to a universal solution - and offer 3rd shot at worse



Just a note: BC is still at well over 50,000 shots / day with a fairly large stockpile

[Anonymous]

This is being pressed now - they will get to a universal solution - and offer 3rd shot at worse

As long as people can travel without quarantine.

[Odinson]

How long does the vaccine protection last?



I´m guessing not very long since they are planning on the 3rd shot.







The virus will still be here and you are gonna need another vaccine and another after that.





What is the end game?



Taking vaccines for the rest of your life?

[cc]

Possibly so. In that way, it's a corona .. Flu shots are not only offered annually but varied to tackle new variants



It will be the same for covid - upgraded for existing variants.



The selfish unvaxxed are the people most likely to catch it thus most likely the ones to spawn new and more aggressive variants that can affect everyone else

[Anonymous]

How long does the vaccine protection last?



I´m guessing not very long since they are planning on the 3rd shot.







The virus will still be here and you are gonna need another vaccine and another after that.





What is the end game?



Taking vaccines for the rest of your life?

An annual shot perhaps. That really isn't a big deal.

[Anonymous]

Possibly so. In that way, it's a corona .. Flu shots are not only offered annually but varied to tackle new variants



It will be the same for covid - upgraded for existing variants.



The selfish unvaxxed are the people most likely to catch it thus most likely the ones to spawn new and more aggressive variants that can affect everyone else

Those of us who are vaccinated will probably be okay even if we do catch COVID variants.