Australian scientists said Tuesday they have successfully developed a lab-grown version of the coronavirus – the first such version outside of China – which is seen as a "significant breakthrough."
Researchers from the Peter Doherty Institute for Infection and Immunity in Melbourne will share their discovery with the World Health Organization (WHO) in the hope it could improve efforts to treat and diagnose the virus, which has killed 132 people and infected nearly 6,000 in China and abroad.
The Doherty Institute's Virus Identification Laboratory head, Dr. Julian Druce, said having the real virus could be used as "control material" for testing while describing it as a "game-changer," according to the Telegraph.
Scientists have reportedly grown a copy of the virus from an infected patient from a sample sent to them last Friday, the Telegraph said.
The lab-grown recreation is expected to be involved in an early-diagnosis test that could detect the coronavirus in people who have yet to display symptoms, which is important because the virus is currently able to spread without visible symptoms, according to the BBC.
An antibody test will enable us to retrospectively test suspected patients so we can gather a more accurate picture of how widespread the virus is, and consequently, among other things, the true mortality rate," Dr. Mike Catton, who works at the Institute told the outlet. "It will also assist in the assessment of [the] effectiveness of trial vaccines."
Quote from: "cc"
Australian scientists said Tuesday they have successfully developed a lab-grown version of the coronavirus – the first such version outside of China – which is seen as a "significant breakthrough."
Researchers from the Peter Doherty Institute for Infection and Immunity in Melbourne will share their discovery with the World Health Organization (WHO) in the hope it could improve efforts to treat and diagnose the virus, which has killed 132 people and infected nearly 6,000 in China and abroad.
The Doherty Institute's Virus Identification Laboratory head, Dr. Julian Druce, said having the real virus could be used as "control material" for testing while describing it as a "game-changer," according to the Telegraph.
Scientists have reportedly grown a copy of the virus from an infected patient from a sample sent to them last Friday, the Telegraph said.
The lab-grown recreation is expected to be involved in an early-diagnosis test that could detect the coronavirus in people who have yet to display symptoms, which is important because the virus is currently able to spread without visible symptoms, according to the BBC.
An antibody test will enable us to retrospectively test suspected patients so we can gather a more accurate picture of how widespread the virus is, and consequently, among other things, the true mortality rate," Dr. Mike Catton, who works at the Institute told the outlet. "It will also assist in the assessment of [the] effectiveness of trial vaccines."
:smiley_thumbs_up_yellow_ani:
FURTHER & maybe extremely important
Apparently S Korea & China tested using 30 with virus and 30 without it
After 6 days, all 30 with virus had no symptoms
More testing needed - but it is so simple a remedy ... seems China is using it now
It's the age old malaria drug (since ww2) that many of us take before going to areas where malaria is present chloroquine, hydroxychloroquine .. brand name Plaquenil .. a nickle a pill
Don't see link - but I just heard interview on TV with the co-leader of the project
According to South Korean and China human treatment guidelines, chloroquine
Medical doctors may be reluctant to prescribe chloroquine to treat COVID-19 since it is not FDA approved
The United States of America and other countries should immediately authorize and indemnify medical doctors for prescribing chloroquine to treat COVID-19. We must explore whether chloroquine can safely serve as a preventative measure prior to infection of COVID-19 to stop further spread of this highly contagious virus."
It is one of the oldest, most reliable, long ago fully tested drugs in use today
At least 10 clinical trials are currently looking at the potential use of chloroquine as an option for combating the novel coronavirus.
UK has already moved to outlaw hoarding of it .. so I suspect there is something to this one
It proved effective to cure existing Sars ... What are we waiting for??
It is used to treat existing - It is not a vaccine
This coronavirus has been blown way out of proportion. Having said that, I hope they get a vaccine out to the public ASAP.
Actually it hasn't been exaggerated . Not at all in fact. If allowed to proliferate at current speed it would hit everyone. You know what curves look like and close to vertical is where we would be going .. everyone would get it.
That said, Bernie's young puppet types who would love to take a light hit and see boomers gone .. would love it and take power :wink:
Quote from: "cc"
That said, Bernie's young puppet types who would love to take a light hit and see boomers gone .. would love it and take power :wink:
Shutting down the global economy for a flu bug?? I am working from home now as of yesterday. What if I did catch the coronavirus. I'm 35, I don't smoke and I'm in excellent physical health. I miss a week or two of work and then I'm healthy again. People over 65 and those with certain medical conditions should self isolate. Everybody else will be fine.
Quote from: "Shen Li"
Quote from: "cc"
That said, Bernie's young puppet types who would love to take a light hit and see boomers gone .. would love it and take power :wink:
Shutting down the global economy for a flu bug?? I am working from home now as of yesterday. What if I did catch the coronavirus. I'm 35, I don't smoke and I'm in excellent physical health. I miss a week or two of work and then I'm healthy again. People over 65 and those with certain medical conditions should self isolate. Everybody else will be fine.
I would not be so confident kid. You can have permanent lung damage even if you do recover. At this stage in the game it's a bit too late for flattening the curve with it spiralling out of control in Europe. We got to skip all the regulatory bullshit and get a vaccine out there yesterday.
vacine will be very slow I read .. and thus useless .. although making time exemptions could help at some point
However, likely effective "treatment type" meds can be now to greatly reduce symptoms if they get off their asses and approve usage of drug(s) long ago approved for many other usages .. drugs proven to be quite safe in fact
We are not at the old point of "future" .. we are now at the point of "now"
Quote from: "cc"
However, likely effective "treatment type" meds can be now to greatly reduce symptoms if they get off their asses and approve usage of drug(s) long ago approved for many other usages .. drugs proven to be quite safe in fact
We are not at the old point of "future" .. we are now at the point of "now"
I hope they get approved very soon.
University of Queensland Centre for Clinical Research director Professor David Paterson told news.com.au today they have seen two drugs used to treat other conditions wipe out the virus in test tubes.
He said one of the medications, given to some of the first people to test positive for COVID-19 in Australia, had already resulted in "disappearance of the virus" and complete recovery from the infection.
"Patients would end up with no viable coronavirus in their system at all after the end of therapy."
The drugs are both already registered and available in Australia.
"What we want to do at the moment is a large clinical trial across Australia, looking at 50 hospitals, and what we're going to compare is one drug, versus another drug, versus the combination of the two drugs," Prof Paterson said.
Given their history, researchers have a "long experience of them being very well tolerated" and there are no unexpected side effects.
"We're not on a flat foot, we can sort of move ahead very rapidly with enrolling Australians in this trial," Prof Paterson said.
"It's the question we all have – we know it's coming now, what is the best way to treat it?"
Prof Paterson said positive experiences in the fight against coronavirus have already been recorded overseas, citing China and Singapore. His research team are confident they can start getting the drugs to patients in a very safe way on home soil.
"We want to give Australians the absolute best treatment rather than just someone's guesses or someone's anecdotal experiences from a few people," Prof Paterson told news.com.au.
He said they hope to be enrolling patients by the end of March.
"And that way, if we can test it in this first wave of patients, we do fully expect that there are going to be ongoing infections for months and months ahead, and therefore we'll have the best possible information to treat subsequent patients," Prof Paterson said.
"That's really our aim, to get real world experience in Australia."
He said the trouble with the data coming from China was that it wasn't really gathered "in a very controlled way", given they were the epicentre of the coronavirus outbreak at the time.
"Things were just chaotic," Prof Paterson said.
"There were these emergency hospitals being built and the system really being very, very stretched."
One of the two medications is a HIV drug, which has been superseded by "newer generation" HIV drugs, and the other is an anti-malaria drug called chloroquine which is rarely used and "kept on the shelf now" due to resistance to malaria.
He said the researchers want to study them in a "very meaningful way" against the coronavirus to "try and alleviate that anxiety of Australians".
"There have already been patients treated with these in Australia and there's been successful outcomes but it hasn't been done in a controlled or a comparative way," Prof Paterson said.
The drugs would be given orally, as tablets.
Prof Paterson said patients would be asked to participate "as soon as they're admitted" to hospital with the aim of beginning treatment "very early on in their illness".
He said the research was sparked by Chinese patients, who were first given the drug in Australia, showing their doctors information on the internet about the treatment used overseas.
"Our doctors were very, very surprised that a HIV drug could actually work against the novel coronavirus and there was a bit of scepticism," he said.
"That first wave of Chinese patients we had (in Australia), they all did very, very well when they were treated with the HIV drug.
"That's reassuring ... that we're onto something really good here."
https://www.heraldsun.com.au/lifestyle/health/coronavirus-australia-queensland-researchers-find-cure-want-drug-trial/news-story/93e7656da0cff4fc4d2c5e51706accb5
That's the one I mentioned in this or the other thread a few days ago
I have the hope that Trump's tomorrow morning announcement will be the authorizing of use of hydroxychloroquine or chloroquine
Another test, this time France showed great promise in treating it .. it's a treatment for those who have the illness, not vaccine
Quote from: "TheVancouverGuy"
He said one of the medications, given to some of the first people to test positive for COVID-19 in Australia, had already resulted in "disappearance of the virus" and complete recovery from the infection.
"Patients would end up with no viable coronavirus in their system at all after the end of therapy."
The drugs are both already registered and available in Australia.
"What we want to do at the moment is a large clinical trial across Australia, looking at 50 hospitals, and what we're going to compare is one drug, versus another drug, versus the combination of the two drugs," Prof Paterson said.
Given their history, researchers have a "long experience of them being very well tolerated" and there are no unexpected side effects.
"We're not on a flat foot, we can sort of move ahead very rapidly with enrolling Australians in this trial," Prof Paterson said.
"It's the question we all have – we know it's coming now, what is the best way to treat it?"
Prof Paterson said positive experiences in the fight against coronavirus have already been recorded overseas, citing China and Singapore. His research team are confident they can start getting the drugs to patients in a very safe way on home soil.
"We want to give Australians the absolute best treatment rather than just someone's guesses or someone's anecdotal experiences from a few people," Prof Paterson told news.com.au.
He said they hope to be enrolling patients by the end of March.
"And that way, if we can test it in this first wave of patients, we do fully expect that there are going to be ongoing infections for months and months ahead, and therefore we'll have the best possible information to treat subsequent patients," Prof Paterson said.
"That's really our aim, to get real world experience in Australia."
He said the trouble with the data coming from China was that it wasn't really gathered "in a very controlled way", given they were the epicentre of the coronavirus outbreak at the time.
"Things were just chaotic," Prof Paterson said.
"There were these emergency hospitals being built and the system really being very, very stretched."
One of the two medications is a HIV drug, which has been superseded by "newer generation" HIV drugs, and the other is an anti-malaria drug called chloroquine which is rarely used and "kept on the shelf now" due to resistance to malaria.
He said the researchers want to study them in a "very meaningful way" against the coronavirus to "try and alleviate that anxiety of Australians".
"There have already been patients treated with these in Australia and there's been successful outcomes but it hasn't been done in a controlled or a comparative way," Prof Paterson said.
The drugs would be given orally, as tablets.
Prof Paterson said patients would be asked to participate "as soon as they're admitted" to hospital with the aim of beginning treatment "very early on in their illness".
He said the research was sparked by Chinese patients, who were first given the drug in Australia, showing their doctors information on the internet about the treatment used overseas.
"Our doctors were very, very surprised that a HIV drug could actually work against the novel coronavirus and there was a bit of scepticism," he said.
"That first wave of Chinese patients we had (in Australia), they all did very, very well when they were treated with the HIV drug.
"That's reassuring ... that we're onto something really good here."
https://www.heraldsun.com.au/lifestyle/health/coronavirus-australia-queensland-researchers-find-cure-want-drug-trial/news-story/93e7656da0cff4fc4d2c5e51706accb5
It doesnt matter how much it costs. let's get those drugs out to the world ASAP.
hydroxychloroquine or chloroquine, if tests done prove true, is an oldy ... costs a nickle a pill
Since I mentioned these a few days ago - 2 more small tests have supported initial tests
Quote from: "cc"
Since I mentioned these a few days ago - 2 more small tests have supported initial tests
So, if people that get the virus in Australia, they will be okay.
Not sure what you mean
Is Oz more lax on meds?
Those 2 are long ago approved in every country .. for other uses ... malaria etc.
We took it before going to Philippines and Thailand - a malaria prophylactic
Quote from: "cc"
Is Oz more lax on meds?
Those 2 are long ago approved in every country .. for other uses ... malaria etc.
We took it before going to Philippines and Thailand - a malaria prophylactic
No, I mean they know it works for coronavirus. So the problem is solved.
Aw. May need more testing - but early and fairly small tests were perfect results
France tested it and released great results this morning .. I've heard of 4 tests so far, all small numbers like 25 - 40 people
BTW - not Ox. Oz grew copy of virus - = slow progress toward vaccine
Sorry, I combined 2 different methods in one thread - sorry to confuse
Quote from: "cc"
France tested it and released great results this morning .. I've heard of 4 tests so far, all small numbers like 25 - 40 people
How about Canada and the USA?
Quote from: "Fashionista"
Quote from: "cc"
France tested it and released great results this morning .. I've heard of 4 tests so far, all small numbers like 25 - 40 people
How about Canada and the USA?
not aware of any .. France is today - I forget where others tested .. may be above or in another thread
Quote from: "cc"
Quote from: "Fashionista"
Quote from: "cc"
France tested it and released great results this morning .. I've heard of 4 tests so far, all small numbers like 25 - 40 people
How about Canada and the USA?
not aware of any .. France is today - I forget where others tested .. may be above or in another thread
I hope North America gets some good news like that very soon.
Have no idea what it is about, but Trump hinted strongly at a major announcement in morning
Almost too much to hope for .. but I will anyhow
%^&*#$% China
The more I learn about the things they did and did not do, the madder I get
Quote from: "cc"
Almost too much to hope for .. but I will anyhow
Oh I hope it's something similar to what's happening in Australia.
Don't be confused - Oz was growing a copy - a start but not a fast cure for sure
chloroquine is used for those WITH virus .. vs long process to develop a vaccine to prevent
There were posts by scientists that China used chloroquine .... China quickly moved to take care of them and their posts
More China games are coming to light every day now - They still will not allow WHO or CDC unfettered access to info so they can help ... while 1000s die every day
Apparently Hydroxychloroquine has less side effects than chloroquine
HHS secretary is on TV now, and not poo pooing these 2 - he's the one who said the above .. but they are not ready to go ahead yet
Quote from: "cc"
chloroquine is used for those WITH virus .. vs long process to develop a vaccine to prevent
There were posts by scientists that China used chloroquine .... China quickly moved to take care of them and their posts
More China games are coming to light every day now - They still will not allow WHO or CDC unfettered access to info so they can help ... while 1000s die every day
I understand it's a treatment for those that have it and not a vaccination for those that don't.
Gotta go - have a good night
I have the feeling a lot is going to change very soon ... and much more info is coming to light fast
Quote from: "cc"
I have the feeling a lot is going to change very soon ... and much more info is coming to light fast
Goodnight cc..
Let us know what you find out.