COVID-19 >>"True and Helpful" Covid Information Thread

[Blazor]

How crazy is it that these protesters forgot all about social distancing. Madness.

But notice they didnt forget their "masks"  

[Anonymous]

How crazy is it that these protesters forgot all about social distancing. Madness.

Rioting first, pandemic a distant second.

[Anonymous]

How crazy is it that these protesters forgot all about social distancing. Madness.

But notice they didnt forget their "masks"  

Antifa never forgets them.

[Anonymous]

This looks promising even though treatments won't be available for nine months.



Human trials approved for B.C. drug company to treat COVID-19



A Vancouver-based drug repurposing company will conduct human trials on patients with acute lung injury in the U.S. and Canada.



Chris Moreau, CEO of Algernon Pharmaceuticals Inc., said the U.S. Food and Drug Administration approved the company's application on June 3 for a human study of its repurposed drug Ifenprodil as a potential therapeutic treatment for patients with COVID-19.



Ifenprodil is a generic drug developed in the early 1970s and approved for human use in Japan and South Korea to treat neurological conditions like vertigo. Algernon has filed a method of use patent on the drug and now has exclusive rights.



"If we see Ifenprodil acting this way in an animal study for H5N1 we may expect to see similar results in a human study for COVID," he said.



Moreau said the phase two human trial would be among 100 COVID-19 patients in acute-care settings in research hospitals in Canada and the U.S. and was expected to start within two months. The patients will get the drug two times a day for three weeks through intravenous fluid.



If that trial is a success, a phase three trial on a larger group of patients would go ahead in September.



Moreau said that if all trials work the drug could be available in the first three months of 2021.

https://vancouversun.com/news/human-trials-approved-for-b-c-drug-company-to-treat-covid-19">https://vancouversun.com/news/human-tri ... t-covid-19">https://vancouversun.com/news/human-trials-approved-for-b-c-drug-company-to-treat-covid-19

[cc]

How crazy is it that these protesters forgot all about social distancing. Madness.

But notice they didnt forget their "masks"  

Antifa never forgets them.

They were practicing for Covid years ahead  .. amazing foresight

[Anonymous]

How crazy is it that these protesters forgot all about social distancing. Madness.

But notice they didnt forget their "masks"  

Antifa never forgets them.

They were practicing for Covid years ahead  .. amazing foresight

lol, of course.

[Anonymous]

Oh my, testing doesn't mean that much.



Main coronavirus test produces 'false negatives' at least 20% of the time, study shows



The primary type of testing for the novel coronavirus around the world, including Canada, produces "false-negative" results at least 20 per cent of the time, researchers from Johns Hopkins University found.





According to a study published in the Annals of Internal Medicine in May, the false-negative rate of RT-PCR testing used to detect the novel coronavirus changes depending on where a person is in the timeline of the infection cycle.



On day 1 of an infection, the test is completely ineffective at detecting the virus, while on day 8 of infection the test produces false negatives 20 per cent of the time, the study found. The rate of false-negatives then increases every day afterward.



On day five of infection, which is when symptoms of COVID-19 typically begin to appear, and when people are often encouraged to seek out testing, the study found the false-negative rate is 38 per cent.



"The probability of a false-negative result varies throughout the course of infection," said Dr. Lauren Kucirka, a resident physician at Johns Hopkins and co-author of the study.



"If you test someone immediately after they're infected, the false-negative rate is very high."

https://globalnews.ca/news/7045805/coronavirus-test-false-negative-study/">https://globalnews.ca/news/7045805/coro ... ive-study/">https://globalnews.ca/news/7045805/coronavirus-test-false-negative-study/

[Anonymous]

T cells found in COVID-19 patients 'bode well' for long-term immunity



Immune warriors known as T cells help us fight some viruses, but their importance for battling SARS-CoV-2, the virus that causes COVID-19, has been unclear. Now, two studies reveal infected people harbor T cells that target the virus—and may help them recover. Both studies also found some people never infected with SARS-CoV-2 have these cellular defenses, most likely because they were previously infected with other coronaviruses.



"This is encouraging data," says virologist Angela Rasmussen of Columbia University. Although the studies don't clarify whether people who clear a SARS-CoV-2 infection can ward off the virus in the future, both identified strong T cell responses to it, which "bodes well for the development of long-term protective immunity," Rasmussen says. The findings could also help researchers create better vaccines.



The more than 100 COVID-19 vaccines in development mainly focus on another immune response: antibodies. These proteins are made by B cells and ideally latch onto SARS-CoV-2 and prevent it from entering cells. T cells, in contrast, thwart infections in two different ways. Helper T cells spur B cells and other immune defenders into action, whereas killer T cells target and destroy infected cells. The severity of disease can depend on the strength of these T cell responses.

https://www.sciencemag.org/news/2020/05/t-cells-found-covid-19-patients-bode-well-long-term-immunity">https://www.sciencemag.org/news/2020/05 ... m-immunity">https://www.sciencemag.org/news/2020/05/t-cells-found-covid-19-patients-bode-well-long-term-immunity



T-cells could be more effective than antibodies.

[Gaon]

Breakthrough at Israeli lab as coronavirus vaccine passes first stage



A coronavirus vaccine developed in Israel was tested successfully on lab hamsters and shows promise as a potential cure for the pandemic, Israel Hayom reported Sunday.



The Institute for Biological Research (IIBR) published a report Friday showing how the new vaccine being developed in Israel successfully inoculated hamsters against the coronavirus.



The vaccination of hamsters "results in rapid and potent induction of neutralizing antibodies against" the coronavirus, the researchers wrote, adding that the lungs of infected hamsters displayed extensive tissue damage while "the immunized hamsters lungs showed only minor lung pathology, and no viral load."



The scientists concluded that their method with a single dose vaccination is "a safe, efficacious and protective vaccine against SARS-CoV-2 infection. These results pave the way for further examination ... in clinical trials as a vaccine against SARS-CoV-2."



The IIBR noted that more than 90 vaccines are being worked on around the world using a variety of technologies, none of which have yet been approved. The Israeli team used a different approach using the "recombinant replicating virus" method that was originally discovered by two American researchers.



Prime Minister Benjamin Netanyahu announced last week that Israel has signed an agreement with the American bio-technology company Moderna to acquire vaccines being worked on by the Cambridge, Massachusetts-based firm.



"The company is advancing its development. They say they can achieve it in the middle of next year, we hope they will succeed, although there is no guarantee of that, but we want to get these vaccines quickly if and when they are developed," Netanyahu said. "It puts us in a very good place in the world."

https://worldisraelnews.com/breakthrough-at-israeli-lab-as-coronavirus-vaccine-passes-first-stage/">https://worldisraelnews.com/breakthroug ... rst-stage/">https://worldisraelnews.com/breakthrough-at-israeli-lab-as-coronavirus-vaccine-passes-first-stage/



I don't know if Israel's quest for a vaccine is ahead of other countries.

[cc]

Based on past performance, I's guess a 50% chance Israel with do it first

[Anonymous]

Breakthrough at Israeli lab as coronavirus vaccine passes first stage



A coronavirus vaccine developed in Israel was tested successfully on lab hamsters and shows promise as a potential cure for the pandemic, Israel Hayom reported Sunday.



The Institute for Biological Research (IIBR) published a report Friday showing how the new vaccine being developed in Israel successfully inoculated hamsters against the coronavirus.



The vaccination of hamsters "results in rapid and potent induction of neutralizing antibodies against" the coronavirus, the researchers wrote, adding that the lungs of infected hamsters displayed extensive tissue damage while "the immunized hamsters lungs showed only minor lung pathology, and no viral load."



The scientists concluded that their method with a single dose vaccination is "a safe, efficacious and protective vaccine against SARS-CoV-2 infection. These results pave the way for further examination ... in clinical trials as a vaccine against SARS-CoV-2."



The IIBR noted that more than 90 vaccines are being worked on around the world using a variety of technologies, none of which have yet been approved. The Israeli team used a different approach using the "recombinant replicating virus" method that was originally discovered by two American researchers.



Prime Minister Benjamin Netanyahu announced last week that Israel has signed an agreement with the American bio-technology company Moderna to acquire vaccines being worked on by the Cambridge, Massachusetts-based firm.



"The company is advancing its development. They say they can achieve it in the middle of next year, we hope they will succeed, although there is no guarantee of that, but we want to get these vaccines quickly if and when they are developed," Netanyahu said. "It puts us in a very good place in the world."

https://worldisraelnews.com/breakthrough-at-israeli-lab-as-coronavirus-vaccine-passes-first-stage/">https://worldisraelnews.com/breakthroug ... rst-stage/">https://worldisraelnews.com/breakthrough-at-israeli-lab-as-coronavirus-vaccine-passes-first-stage/



I don't know if Israel's quest for a vaccine is ahead of other countries.

There doesn't seem to be no chance of any vaccine before the end of 2020.

 

[Anonymous]

Others around seniors should get a COVID-19 vaccine when it becomes available.



COVID-19 vaccine may not work in older people, experts say



TORONTO -- A vaccine against COVID-19 may not be as effective in older people who are most at risk of suffering complications and dying from the disease, according to U.K. researchers.



However, some experts say immunizing those around the elderly may help protect them.

https://www.ctvnews.ca/health/coronavirus/covid-19-vaccine-may-not-work-in-older-people-experts-say-1.4997928">https://www.ctvnews.ca/health/coronavir ... -1.4997928">https://www.ctvnews.ca/health/coronavirus/covid-19-vaccine-may-not-work-in-older-people-experts-say-1.4997928

[cc]

That's actually a wide look at possibilities .. posturing, totally theoretical, not scientific and not scientifically informational



Yes, some of the things mentioned are possible (as is pretty much anything) and "may" happen, but it's parlor talk / conjecture at this point in time ... in short, total guesswork

[Anonymous]

That's actually a wide look at possibilities .. posturing, totally theoretical, not scientific and not scientifically informational



Yes, some of the things mentioned are possible (as is pretty much anything), but it's parlor talk at this point

hmmm

[cc]

I'm not trying to shoot it down - rather what I'm trying to say is that I wish medicine, when speaking to the general population,  would stick to what it knows so far to be true, not to what it does not yet know to be true



The person could be right, but is merely theorizing at this point... thinking out loud



We have had so much bad info from "experts" taking one piece of info and extrapolating it into more than it is and done harm .. most of their theories to date have hurt more than they have helped